Publisher: Academic Press
* Number Of Pages: 584
* Publication Date: 2005-11-22
* Sales Rank: 42012
* ISBN / ASIN: 0120884429
* EAN: 9780120884421
* Binding: Hardcover
* Manufacturer: Academic Press
* Studio: Academic Press
* Average Rating: 5
* Total Reviews: 3
Book De******ion:
Quote:
This abridged version of the bestselling reference Handbook of Stem Cells, Two-Volume Set attempts to incorporate all the essential subject matter of the original two-volume edition in a single volume. The material has been reworked in an accessible format suitable for students and general readers interested in following the latest advances in stem cells, including full color presentation throughout. Although some extra language and chapters have been deleted, rigorous effort has been made to retain from the original two-volume set the material pertinent to the understanding of this exciting area of biology.
The organization of the book remains largely unchanged, combining the prerequisites for a general understanding of !!!!! and embryonic stem cells; the tools, methods, and experimental protocols needed to study and characterize stem cells and progenitor populations; as well as a presentation by the world's experts of what is currently known about each specific organ system.
* Full-color presentation througout
* Each chapter begins with 3-5 defined glossary terms, and all of the terms are collected in a comprehensive list within the book
* References have been eliminated - now there are about 10 bibliographic entries per chapter
Contents
PHP Code:
Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix
PREFACE. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xv
Robert Lanza
FOREWORD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xvii
Bruce Alberts
Embryonic Stem Cells in Perspective . . . . . . . . . . . . . . xix
Janet Rossant
Embryonic Stem Cells Versus !!!!! Stem Cells:
Some Seemingly Simple Questions . . . . . . . . . . . . . . . xxiii
Darwin J. Prockop
‘Stemness’: Definitions, Criteria, and Standards. . . . . . . xxv
Chad Cowen and Douglas A. Melton
PART ONE
Introduction to stem cells
1. Present Perspective and Future Challenges . . . . . . . . . 1
R. L. Gardner
2. The Development of Epithelial Stem Cell
Concepts. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
C. S. Potten and J. W. Wilson
3. “!!!!!” Stem Cells: Tissue Specific or Not? . . . . . . . 23
Catherine M. Verfailli
PART TWO
Basic biology/mechanisms
4. Molecular ****s of Pluripotency . . . . . . . . . . . . . . . 29
Fatima Cavaleri and Hans Schöler
5. Stem Cell Niches . . . . . . . . . . . . . . . . . . . . . . . . . . 43
D. Leanne Jones and Margaret T. Fuller
6. Mechanisms of Stem Cell Self-Renewal . . . . . . . . . . 55
Hitoshi Niwa
7. Cell Cycle Regulators in Stem Cells. . . . . . . . . . . . . 63
Tao Cheng and David T. Scadden
8. Epigenetic Mechanisms of Cellular Memory
During Development . . . . . . . . . . . . . . . . . . . . . . . . 69
N. D. Montgomery, T. Magnuson, and S. Bultman
9. Cell Fusion and the Differentiated State . . . . . . . . . . 81
Penny Johnson and Peter W. Andrews
10. How Cells Change Their Phenotype . . . . . . . . . . . . . 87
David Tosh and Marko E. Horb
11. Nuclear Cloning and Epigenetic
Reprogramming . . . . . . . . . . . . . . . . . . . . . . . . . . . 93
Zhongde Wang, Alexander Meissner, and
Rudolf Jaenisc
PART THREE
Tissue and organ development
12. Differentiation in Early Development . . . . . . . . . . . 101
Susana M. Chuva de Sousa Lopes and
Christine Mummery
13. Primordial Germ Cells in Mouse and Human . . . . . 111
Anne McLaren
14. Stem Cells in Extraembryonic Lineages . . . . . . . . . 117
Tilo Kunath and Janet Rossant
15. Amniotic Fluid Derived Pluripotential Cells . . . . . . 127
M. Minhaj Siddiqui and Anthony Atala
16. Cord Blood Hematopoietic Stem and Progenitor
Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133
Hal E. Broxmeyer
17. Neurogenesis in the Vertebrate Embryo . . . . . . . . . 139
Chris Kintner and Naoko Koyano-Nakagawa
18. The Nervous System . . . . . . . . . . . . . . . . . . . . . . . 149
Lorenz Studer
19. Neuronal Progenitors in the !!!!! Brain: From
Development to Regulation . . . . . . . . . . . . . . . . . . 157
Christian Mirescu and Elizabeth Gould
20. Sensory Epithelium of the Eye and Ear. . . . . . . . . . 161
Connie Cepko and Donna M. Fekete
21. Epithelial Skin Stem Cells . . . . . . . . . . . . . . . . . . . 169
Tudorita Tumbar and Elaine Fuchs
22. The Ontogeny of the Hematopoietic System . . . . . . 177
Malcolm A. S. Moore
23. Hematopoietic Stem Cells . . . . . . . . . . . . . . . . . . . 187
George Q. Daley
24. Cell Differentiation in the Skeleton . . . . . . . . . . . . 191
Gerard Karsenty
25. Human Vascular Progenitor Cells . . . . . . . . . . . . . . 195
Sharon Gerecht-Nir and Joseph Itskovitz-Eldor
26. Multipotent !!!!! Progenitor Cells . . . . . . . . . . . . . 201
Alaa Adassi and Catherine M. Verfaillie
27. Mesenchymal Stem Cells. . . . . . . . . . . . . . . . . . . . 205
Arnold I. Caplan
28. Skeletal Muscle Stem Cells . . . . . . . . . . . . . . . . . . 211
Mark A. LaBarge and Helen M. Blau
29. Stem Cells and the Regenerating Heart. . . . . . . . . . 217
Nadia Rosenthal and Maria Paola Santini
30. Potential of ES Cell Differentiation Culture for
Vascular Biology . . . . . . . . . . . . . . . . . . . . . . . . . . 221
Hiroshi Hisatsune, Nobuyuki Kondoh,
Jun Yamashita, Satomi Nishikawa, and
Shin-Ichi Nishikawa
31. Cell Lineages and Stem Cells in the Embryonic
Kidney . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 227
Gregory R. Dressler
32. !!!!! Liver Stem Cells . . . . . . . . . . . . . . . . . . . . . 237
Craig Dorrell and Markus Grompe
33. Pancreatic Stem Cells . . . . . . . . . . . . . . . . . . . . . . 245
Yuval Dor and Douglas A. Melton
34. Stem Cells in the Gastrointestinal Tract . . . . . . . . . 253
Sean L. Preston, Natalie C. Direkze,
Nicholas A. Wright, and Mairi Brittan
PART FOUR
Methods
35. Characterization of Human Embryonic Stem
Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 265
Holly Young and Melissa K. Carpenter
36. Isolation and Maintenance of Murine Embryonic
Stem Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 269
Martin Evans
37. Isolation, Characterization, and Maintenance of
Primate ES Cells . . . . . . . . . . . . . . . . . . . . . . . . . . 275
Michal Amit and Joseph Itskovitz-Eldor
38. Approaches for Derivation and Maintenance of
Human ES Cells: Detailed Procedures and
Alternatives. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 287
Irina Klimanskaya and Jill McMahon
39. Isolation and Maintenance of Murine Embryonic
Germ Cell Lines . . . . . . . . . . . . . . . . . . . . . . . . . . 299
Gabriela Durcova-Hills and Anne McLaren
40. Derivation and Differentiation of Human
Embryonic Germ Cells . . . . . . . . . . . . . . . . . . . . . 305
Michael J. Shamblott, Candace L. Kerr,
Joyce Axelman, John W. Littlefield,
Gregory O. Clark. Ethan S. Patterson,
Russell C. Addis, Jennifer N. Kraszewski,
Kathleen C. Kent, and John D. Gearhart
41. Growth Factors and the Serum-Free Culture of
Human Pluripotent Stem Cells . . . . . . . . . . . . . . . . 313
Alice Pébay and Martin F. Pera
42. Feeder-free Culture . . . . . . . . . . . . . . . . . . . . . . . . 317
Holly Young, Chunhui Xu, and
Melissa K. Carpenter
43. Genetic Manipulation of Human Embryonic
Stem Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 325
Yoav Mayshar and Nissim Benvenisty
44. Homologous Recombination in Human
Embryonic Stem Cells . . . . . . . . . . . . . . . . . . . . . . 331
Thomas P. Zwaka and James A. Thomson
45. Surface Antigen Markers . . . . . . . . . . . . . . . . . . . . 337
Jonathan S. Draper and Peter W. Andrews
46. Lineage Marking . . . . . . . . . . . . . . . . . . . . . . . . . . 343
Andras Nagy
47. Genomic Reprogramming . . . . . . . . . . . . . . . . . . . 349
M. A. Surani
48. Identification and Maintenance of Cell Lineage
Progenitors Derived from Human ES Cells . . . . . . . 355
Susan Hawes and Martin F. Pera
49. Isolation and Characterization of Hematopoietic
Stem Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363
Gerald J. Spangrude and William B. Slayton
50. Microarray Analysis of Stem Cells and
Differentiation . . . . . . . . . . . . . . . . . . . . . . . . . . . . 369
Howard Y. Chang, James A. Thomson, and
Xin Chen
51. Zebrafish and Stem Cell Research . . . . . . . . . . . . . 377
K. Rose Finley and Leonard I. Zon
PART FIVE
Applications
52. Neural Stem Cells: Therapeutic Applications in
Neurodegenerative Diseases . . . . . . . . . . . . . . . . . . 383
Rodolfo Gonzalez, Yang D. Teng, Kook I. Park,
Jean Pyo Lee, Jitka Ourednik, Vaclav Ourednik,
Jaimie Imitola, Franz-Josef Mueller,
Richard L. Sidman, and Evan Y. Snyder
53. Spinal Cord Injury. . . . . . . . . . . . . . . . . . . . . . . . . 395
John W. McDonald, Daniel Becker, and
James Huettner
54. Use of Embryonic Stem Cells to Treat Heart
Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 405
Joshua D. Dowell, Robert Zweigerdt,
Michael Rubart, and Loren J. Field
55. Insulin-Producing Cells Derived from Stem Cells:
A Potential Treatment for Diabetes . . . . . . . . . . . . . 411
Gordon C. Weir, Alexandra Haagensen, and
Susan Bonner-Weir
56. Burns and Skin Ulcers . . . . . . . . . . . . . . . . . . . . . . 419
Edward Upjohn, George Varigos, and
Pritinder Kaur
57. Stem Cells and Heart Disease . . . . . . . . . . . . . . . . 425
Piero Anversa, Annarosa Leri, and Jan Kajstura
58. Stem Cells for the Treatment of Muscular
Dystropy: More Than Wishful Thinking? . . . . . . . . 431
Maurilio Sampaolesi, M. Gabriella Cusella De Angelis,
and Giulio Cossu
59. Regeneration of Epidermis from !!!!! Keratinocyte
Stem Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439
Ariane Rochat and Yann Barrandon
60. Orthopaedic Applications of Stem Cells . . . . . . . . . 449
Jerry I. Huang, Jung U. Yoo, and
Victor M. Goldberg
61. Embryonic Stem Cells in Tissue Engineering . . . . . 457
Shulamit Levenberg, Ali Khademhosseini, and
Robert Langer
62. !!!!! Stem Cells in Tissue Engineering . . . . . . . . . 463
Pamela Gehron Robey and Paolo Bianco
63. Stem Cell Gene Therapy . . . . . . . . . . . . . . . . . . . . 471
Brian R. Davis and Nicole L. Prokopishyn
PART SIX
Regulation and ethics
64. The Ethics of Human Stem Cell Research:
Immortal Cells, Moral Selves. . . . . . . . . . . . . . . . . 479
Laurie Zoloth
65. Ethical Considerations . . . . . . . . . . . . . . . . . . . . . . 489
Ronald M. Green
66. Stem Cell Research: Religious Considerations . . . . 495
Margaret A. Farley
67. Stem Cell-****d Therapies: FDA Product and
Preclinical Regulatory Considerations. . . . . . . . . . . 503
Donald W. Fink, Jr. and Steven R. Bauer
68. It’s Not About Curiosity, It’s About Cures
Stem Cell Research: People Help Drive Progress . . . 513
Mary Tyler Moore with S. Robert Levine
69. Patient Advocacy. . . . . . . . . . . . . . . . . . . . . . . . . . 519
Christopher Reeve
Glossary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 521
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 531
[ندعوك للتسجيل في المنتدى أو التعريف بنفسك لمعاينة هذا الرابط]
