Systems Biology in Drug Discovery and Development

(Wiley Series on Technologies for the Pharmaceutical Industry)
Publisher:
ISBN: 047_0261234 |
2011
PDF
380 pages
10.4 MB


This
is the first comprehensive systems biology book to focus on its
applications in drug discovery and development. Using real-world
examples, the book shows how systems biology can be used to enhance
pharmaceutical research and drug development. It highlights essential
components of drug discovery like target identification and validation
and complementary systems approaches like text-mining, large
multi-context datasets and regression modeling. It also provides models
for treatment personalization and methods for applying systems biology
to pharmacokinetics, pharmacodynamics, and candidate biomarker
indentification. Introducing key methods and technical approaches the
book addresses the challe


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