Drug Design of Zinc-Enzyme Inhibitors:
Functional, Structural, and Disease Applications
Drug Design of Zinc-Enzyme Inhibitors:
Functional, Structural, and Disease Applications
Wiley | ISBN:
0470275006 | 2009-08-17 | PDF | 1038 pages | 9 Mb
Brings together
functional and structural informationrelevant to the design of drugs
targeting zinc enzymes
The second most abundant transition element
in living organisms, zinc spans all areas of metabolism, with
zinc-containing proteins offering both established and potential drug
targets. Drug Design of Zinc-Enzyme Inhibitors brings together
functional and structural information relevant to these zinc-containing
targets. With up-to-date overviews of the latest developments field,
this unique and comprehensive text enables readers to understand zinc
enzymes and evaluate them in a drug design context.
With
contributions from the leaders of today's research, Drug Design of
Zinc-Enzyme Inhibitors covers such key topics as:
Major drug targets
like carbonic anhydrases, matrix metalloproteinases, bacterial
proteases, angiotensin-converting enzyme, histone deacetylase, and
APOBEC3G
Roles of recently discovered zinc-containing isozymes in
cancer, obesity, epilepsy, pain management, malaria, and other
conditions
Cross reactivity of zinc-enzyme inhibitors and activators
The extensive use of X-ray crystallography and QSAR studies for
understanding zinc-containing proteins
Clinical applications
An
essential resource for the discovery and development of new drug
molecules, Drug Design of Zinc-Enzyme Inhibitors gives researchers,
professionals, students, and academics the foundation to understand and
work with zinc enzyme inhibitors and activators.
[ندعوك للتسجيل في المنتدى أو التعريف بنفسك لمعاينة هذا الرابط]
[ندعوك للتسجيل في المنتدى أو التعريف بنفسك لمعاينة هذا الرابط]
Functional, Structural, and Disease Applications
Drug Design of Zinc-Enzyme Inhibitors:
Functional, Structural, and Disease Applications
Wiley | ISBN:
0470275006 | 2009-08-17 | PDF | 1038 pages | 9 Mb
Brings together
functional and structural informationrelevant to the design of drugs
targeting zinc enzymes
The second most abundant transition element
in living organisms, zinc spans all areas of metabolism, with
zinc-containing proteins offering both established and potential drug
targets. Drug Design of Zinc-Enzyme Inhibitors brings together
functional and structural information relevant to these zinc-containing
targets. With up-to-date overviews of the latest developments field,
this unique and comprehensive text enables readers to understand zinc
enzymes and evaluate them in a drug design context.
With
contributions from the leaders of today's research, Drug Design of
Zinc-Enzyme Inhibitors covers such key topics as:
Major drug targets
like carbonic anhydrases, matrix metalloproteinases, bacterial
proteases, angiotensin-converting enzyme, histone deacetylase, and
APOBEC3G
Roles of recently discovered zinc-containing isozymes in
cancer, obesity, epilepsy, pain management, malaria, and other
conditions
Cross reactivity of zinc-enzyme inhibitors and activators
The extensive use of X-ray crystallography and QSAR studies for
understanding zinc-containing proteins
Clinical applications
An
essential resource for the discovery and development of new drug
molecules, Drug Design of Zinc-Enzyme Inhibitors gives researchers,
professionals, students, and academics the foundation to understand and
work with zinc enzyme inhibitors and activators.
[ندعوك للتسجيل في المنتدى أو التعريف بنفسك لمعاينة هذا الرابط]
[ندعوك للتسجيل في المنتدى أو التعريف بنفسك لمعاينة هذا الرابط]